It Can Be Done (Carefully)
Because no “standard” stralingsdosis/fractionation exists for ultracentral lung tumors, a hypogefractioneerde radiation (HYPO-RT) approach rather than classic Stereotactic Body Radiotherapie (SBRT) seems prudent because of the proximity of large air.
Abstract (original)
Because no “standard” radiation dose/fractionation exists for ultracentral lung tumors, a hypofractionated radiation (HYPO-RT) approach rather than classic Stereotactic Body Radiation Therapy (SBRT) seems prudent because of the proximity of large airways.1 I prefer 4 Gy × 15 fractions to a total of 60 Gy, extrapolating from the LUSTRE trial2 for primary lung tumors (including central and ultracentral), with a 3-year local control of 87.6% (SBRT) versus 81.2% (HYPO-RT).
Dit artikel is een samenvatting van een publicatie in Int J Radiation Oncology. Voor het volledige artikel, alle details en referenties verwijzen wij u naar de oorspronkelijke bron.
Lees het volledige artikelDOI: 10.1016/j.ijrobp.2025.10.031