Quasi-adiabatische grafietcalorimeter voor absolute dosimetrie bij FLASH-radiotherapie

FLASH radiotherapy using high-energy X-rays combines ultra-high dose-rate irradiation with the physical characteristics of high-energy X-ray beams, achieving a significant reduction in normal tissue biological damage while maintaining sufficient tissue penetration, thereby presenting great potential for clinical translation. However, the absence of a traceable absolute dosimetry method for FLASH X-ray beams remains a substantial limitation to its clinical implementation. This study aims to establish a quasi-adiabatic water-controlled probe-type graphite calorimeter for the absolute measurement of absorbed dose to water in the 10 MV FLASH X-ray beam, to address the current lack of a traceable dosimetry standard for X-ray FLASH radiotherapy.