Risicomodel voor stralingsgeïnduceerde lymfopenie als voorspeller van durvalumab-werkzaamheid bij NSCLC

Severe radiation-induced lymphopenia (RIL) during concurrent chemoradiation therapy (CCRT) for NSCLC has been associated with poorer outcomes and reduced immunotherapy efficacy. Because RIL often develops late during CCRT, identifying patients at risk before treatment may be clinically relevant. This study aimed to develop and validate a nomogram based on pretreatment predictors for severe RIL, and secondarily to explore associations between predicted RIL risk and adjuvant durvalumab-associated survival.