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Clinical Hypothyroidism After Proton Versus Photon Regional Nodal Irradiation: A Prospectieve Correlative Studie Within the RADCOMP Gerandomiseerde Trial

Thyroid dysfunction is a common complication of breast regional nodal irradiation (RNI). Proton therapy has been proposed as a means to spare normal tissue.

Abstract (original)

Thyroid dysfunction is a common complication of breast regional nodal irradiation (RNI). Proton therapy has been proposed as a means to spare normal tissue. We prospectively evaluated the incidence of hypothyroidism in a cohort of patients receiving RNI on a randomized trial comparing proton with photon modalities. A secondary objective was to evaluate the associations between thyroid dose-volume metrics and the risk of subsequent hypothyroidism.

Dit artikel is een samenvatting van een publicatie in Int J Radiation Oncology. Voor het volledige artikel, alle details en referenties verwijzen wij u naar de oorspronkelijke bron.

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DOI: 10.1016/j.ijrobp.2026.02.199