Telomere Length Dynamics As a Biomarker of Individual Radiation Sensitivity and Pneumonitis in Longkanker Patients Receiving Thoracic Radiotherapy
Telomere shortening is a biomarker for genome instability and aging, and the vulnerability of telomeric DNA to oxidative damage suggests its potential role in mediating radiotherapy (RT) side effects.
Abstract (original)
Telomere shortening is a biomarker for genome instability and aging, and the vulnerability of telomeric DNA to oxidative damage suggests its potential role in mediating radiotherapy (RT) side effects. This study evaluates telomere length (TL) as a biomarker for clinical radiosensitivity and adverse outcomes in thoracic RT-treated patients.
Dit artikel is een samenvatting van een publicatie in Int J Radiation Oncology. Voor het volledige artikel, alle details en referenties verwijzen wij u naar de oorspronkelijke bron.
Lees het volledige artikelDOI: 10.1016/j.ijrobp.2025.12.060