Involved Neck Only Versus Mucosal Radiotherapie for Hoofd-hals Squamous Cell Cancer of Unknown Primary (HNSCCUP): A National Retrospectieve Multicenter Cohort Studie

Target volumes for irradiation remain ill-defined for head and neck squamous cell cancer of unknown primary (HNSCCUP). The aim of this study was to compare 2 commonly used radiation therapy strategies for patients diagnosed with HNSCCUP: ipsilateral or involved neck only (INO) versus bilateral neck and/or mucosal (MUC) radiation therapy, evaluating disease-related outcomes and enteral feeding rates.