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Patient-Reported Uitkomsten, Neurocognitive Functioning, and Oncologic Resultaten of Pencil-Beam-Scanning Protonenbundel Therapy for CNS WHO G2 and G3 IDH1-Mutant Diffuse Adult Glioma: A Single Institution Experience

Patients with isocitrate dehydrogenase (IDH)-mutant diffuse glioma achieve long survival after chemoradiotherapie. Proton beam therapy (PBT) can be used for this group to potentially reduce the late neurologic and cognitive complications.

Abstract (original)

Patients with isocitrate dehydrogenase (IDH)-mutant diffuse glioma achieve long survival after chemoradiation therapy. Proton beam therapy (PBT) can be used for this group to potentially reduce the late neurologic and cognitive complications. In the present study, we analyzed the patient-reported outcomes (PROs), objective neurocognitive (NC) functioning, and oncologic results of Central Nervous System World Health Organization (CNS WHO) G2 and G3 diffuse adult glioma treated with PBT in our institution.

Dit artikel is een samenvatting van een publicatie in Int J Radiation Oncology. Voor het volledige artikel, alle details en referenties verwijzen wij u naar de oorspronkelijke bron.

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DOI: 10.1016/j.ijrobp.2025.10.025